Synonym (scientific name)
Ficus deltoidea var. deltoidea Jack
Vernacular name/ local name
Languages |
Name |
Malay |
Mas cotek, serapat angin, telinga beruk, pokok barito, pokok raja ubat, secotek emas |
English |
mistletoe fig, mistletoe rubber plant [1, 2]. |
Character (Color, odour, taste)
The dried leaves are brown in colour, odourless and have slight taste.
Identification
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Plant Morphology
The leaves of F. deltoidea are deltoid with a distinctive forked midrib, leaf length is from 3.0-5.0 cm and width from 3.0-4.0 cm, light green leaf and leathery; upper side shows rusty golden spots and the lower side yellowish green with black spots; leaf base is cuneate and apex shape is rounded or truncate; petiole length 0.7-1.3 cm [3].
Phytochemical screening
Aqueous and methanol extracts of the leaves have been found to contain flavonoids (e.g. vitexin, isovitexin), tannins, polysaccharides and proteins [4,5]. Additionally, the aqueous extract also had flavonoids (e.g. flavan-3-ol, flavone glycosides, chalcone) and others (e.g. phenylalanine, cinnamic acid, proanthocyanidins) [6]. Whereas, the methanolic extract had flavonoids (e.g. moretenol, rutin, narigenin, quercetin) [7,8].
Essential oil of the leaves has been found to contain monoterpenes (e.g. 6-methyl-5-heptane-2-one, mycrene, (Z)-β-ocimene, (E)-β-ocimene, cis-furanoid linalool oxide, trans-furanoid linalool oxide, linalool, limone), sesquiterpenes (e.g. dendrolasine, α-cubebene, cyclosativene, α-ylangene, α-copaene, β-bourbonene, 1,5-diepi-β-bourbonene, β-cubebene, β-elemene, α-gurjunene, α-cis-bergamotene, β-aryophyllene, α-santalene, selina-3,6-diene, cda-trans bergamotene, α-humulene, alloaromadendrene, aciphyllene, germacrene δ, β-selinene, δ-selinene, α-selinene, bicyclogermacrene, α-muurolene, germacrene A, α-amorphene, δ-cadinene, (E,E)- α-farnesene, 2-epi-α-selinene, α-cardinene, cadina-1,4-diene, germacrene β, caryophyllene oxide) and others (e.g. phenol, 2,4-bis(dimethylbenzyl)-6-t-butylphenol, cyanogen, octaethylene glycol, octaethylene glycol monododecyl ether, phthalic acid, 6,10,14-trimethyl-2-pentadecanone, carbonic acid, 1,4,7,10,13,16-hexaoxacyclooctadecane, hexagol, butanoic acid, 2,3-dihydro-1,1,3-trime-1H-indene, 2-(diethylboryl)pheny]-15-crown-5,4-amino-2,6-dimethyl-3-pyridyl-1-adamantanecarboxylate, methyl ester hexadecanoic acid, cyclopenthyl ester 2-methoxybenzoic acid, methyl 16-methylheptadecanoate, 1-propoxy-3,3-diethyltriazene 2-oxide, heptacosane, hexagol) [9,10].
Medicinal uses
Uses described in folk medicine, not supported by experimental or clinical data.
The decoction of the leaf of F. deltoidea is used mainly by women as afterbirth treatment. It is believed that it helps to contract the uterine and the vaginal muscles, improve blood circulation and regain body strength as well as for treating disorders related to the menstrual cycle [11,12].
Anti-inflammatory activity
Standardised methanol and aqueous extracts of F. deltoidea var. deltoidea leaves at concentration of 10 mg/mL were evaluated for anti-inflammatory activity using lipoxygenase (LOX), hyaluronidase (HAase) and TPA-induced oedema assay methods. Vitexin and isovitexin were used as marker for extracts standardization. The result of LOX assay using 15-soybean lipoxygenase show that both methanol and aqueous extracts from both varieties did not display anti-inflammatory activity via LOX mechanism (0-10.35% inhibition). Result for HAase assay indicated that both methanol and aqueous extracts show moderate anti-inflammatory property by inhibiting HAase at 47.05-62.95% and 48.97-51.00% inhibition activity respectively. TPA-induced ear oedema test result shows that anti-inflammatory activity of methanolic extracts (38.74-80.46%) was comparable to apigenin, nordihydroguaiaretic acid, indomethacin, which were used as control. However, aqueous extracts show very low activity in this test (8.38-22.53% inhibition). This study indicates that standardized extracts of leaves of F. deltoidea possess anti-inflammatory properties [13].
Storage
Store below 30°C. Protect from light and moisture.